ULTRASTRUCTURAL AND CYTOCHEMICAL STUDY OF THE RAT HYPERTROPHIED MYOCARDIAL CELLS
- VernacularTitle:大白鼠肥大心肌细胞的超微结构及细胞化学研究
- Author:
Yusheng HAN
;
Yuying CHEN
;
Xiaoping QI
- Publication Type:Journal Article
- Keywords:
Hypertrophied myocardial cells;
Ultrastructure;
Cytochemistry;
Rat
- From:
Acta Anatomica Sinica
1957;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Left ventricular myocardial hypertrophy was produced in the rats by ligation of the abdominal aorta below the diaphragm for seven weeks.Ultrastructurally, it was observed that the nucleus and nucleolus were enlarged, and the density of the chromatin of the hypertrophied myocardial cells was decreased. Free ribosomes and endoplasmic reticulum were increased. Golgi apparatus was well developed and was increased in number.Cytochemically, G6Pase activity was localized in the lumen of the sarcoplasmic reticulum, nuclear envelope and subsarcolemmal cisterns, and it was also positive in the regenerative rough endoplasmic reticulum. TPPase activity appeared in the Golgi apparatus, and it was especially prominent in the Golgi apparatus of the hypertrophied cells.These findings suggest that the protein synthetic activity was increased in the hypertrophied myocardial cells.
