DEVELOPMENT OF PEYER'S PATCHES IN RABBITS
- VernacularTitle:家兔小肠淋巴集结的发生
- Author:
Shunde GAO
;
Hongwei ZHANG
;
Cunren LIU
;
Shiguang YU
- Publication Type:Journal Article
- Keywords:
Development;
Peyer's patches;
Rabbit
- From:
Acta Anatomica Sinica
1953;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
In our experiment the typical structure of Peyer's patches (PP) of rabbits was absent in neonatal animals, but after birth, it developed gradually and rapidly. On the 6 th day, the lymphoid structure of PP appeared and two types of lymphocytes, T and B, were observed in PP. At the same time, there were some microfold cells in the epithelium of the dome. By half a month, the lymphoid structure of PP matured histologically and later on it was more developed and PP gradually increased in size during the growth of the rabbit. The PP of a 3 month old rabbit were similar to those of the mature animals, but no involution of PP appeared at the stage of sexual maturity.The development of PP in rabbits is closely related to the first antigenic stimulation from the intestinal contents, and T, B lymphocytes and macrophages are present at the start of PP formation. In addition, there is no involution of PP in the adult rabbit. These features of PP in rabbits are different from those of the bursa of Fabricius, so it is inappropriate to regard the PP of rabbits as the homologue of the avian bursa of Fabricius.
