EXPERIMENTAL STUDIES ON THE FORMATION OF SECONDARY OPTIC CUP FROM BRAIN WALL OF FROG EMBRYO UNDER THE INDUCTION OF THE PRESUMPTIVE LENS ECTODERM
- VernacularTitle:蛙胚眼预定水晶体诱导脑壁形成次生眼杯的实验研究
- Author:
Xinren LI
;
Qixiang YU
;
Taosheng LI
;
Xicheng WANG
- Publication Type:Journal Article
- Keywords:
Formation of secondary optic cup;
Presumptive lens;
Induction;
Frog embryos
- From:
Acta Anatomica Sinica
1957;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Three types of microscopic operations were used in this study: 1. excision of the optic vesicle alone; 2. after excising the optic vesicle, a piece of forebrain tissue taken from another donor was inserted in between presumptive lens ectoderm and forebrain wall; 3. cut down the optic vesicle and portion of forebrain tissue and replaced them back in situ by turning over 180?. The operations were carried out on Rana nigromaculata at 15 and 16 stages, in order to bring the presumptive lens ectoderm to come into contact directly with the forebrain tissue for the purpose to analyse the possibility of eye cup formation from the brain wall. The results indicate that the forebrain wall which came into contact with the presumptive lens ectoderm could be induced and differentiated into a secondary eye cup or retina. A total of 81 cases of secondary eye cups among 282 operations (28.8%) were observed. The mechanism for the induction and its significance were discussed.
