MORPHOLOGICAL STUDIES OF LARGE DENSE CORE VESICLE NONSYNAPTIC EXOCYTOSIS AND MEMBRANE RECYCLING IN THE TRIGEMINAL SUBNUCLEUS CAUDALIS
- VernacularTitle:三叉神经尾侧亚核大颗粒小泡的非突触部位胞吐及膜再循环的形态观察
- Author:
Peichun ZHU
;
Hong XU
- Publication Type:Journal Article
- Keywords:
Trigeminal subnucleus caudalis: Large dense core vesicle;
Nonsynaptic exocyosis;
Membrane recycling;
Rat
- From:
Acta Anatomica Sinica
1953;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Large dense core vesicle in the trigeminal subnucleus caudalis of the rat has been observed electron microscopically. It is fixed in glutaraldehyde-osmium tetroxide following removal of the skin of the vibrissae areas. The findings of the present study are: 1.Morphological evidence for exocytosis of large dense core vesicle from non-synaptic sites of the axonal terminal has been presented.2. The large coated vesicles equipped with central densities derived from the invagination of the plasma membrane. These observations suggest that membrane recycling occur at location in the terminal via these coated vesicles.3.Some large dense core vesicles may also form the tubular structures which may represent smooth endoplasmic reticulum containing dense material. This study supports the hypothesis that release of the transmitter of the great dense core vesicles occur at nonsynaptic sites by exocytosis.
