A STUDY OF INVADING CAPACITY OF TWO HUMAN TUMOR CELL LINES (ECA-109, BEL-7402) AND NORMAL CHINESE HAMSTER OVARY CELL LINE (CHO)
- VernacularTitle:两种人体肿瘤细胞系(ECa-109、BEL-7402)和正常中国地鼠卵巢细胞系(CHO)体外浸润能力的研究
- Author:
Yanchao QI
;
Fuwen NIU
- Publication Type:Journal Article
- Keywords:
Tumor cell line;
Malignancy;
Invasion in vitro
- From:
Acta Anatomica Sinica
1957;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
The method of combining culture of embryonic chicken mesonephrons or heart fragments with some cells on double layer agar-agar medium is used in this experiment. The authors have investigated with this method invading capacity of malignant esophageal cancer cell line (ECa-109), malignant hepatoma cell line (BEL-7402) and normal diploid Chinese hamster ovary cell line (CHO) to embryonic chicken mesonephrons and heart fragments.The authors have found that both ECa-109 cell line and BEL-7402 cell line have invasive capacity in vitro. The invasive capacity of ECa-109 cells is higher than that of BEL-7402 cells. The normal diploid CHO cells can not invade target organs and show only slight adhesion to them. The capacity for ECa-109 cells or BEL-7402 cells to invade both the embryonic chicken mesonephrons and heart fragment is similar.