STUDIES ON THE CELL KINETICS OF SKIN AND TESTIS IN EXPERIMENTAL ANIMALS
- VernacularTitle:实验动物皮肤和睾丸细胞动力学的研究
- Author:
Fengming GAO
;
Yannan YU
;
Hanying JIANG
- Publication Type:Journal Article
- Keywords:
Tritiated thymidine;
Kinetics;
Spermatogonia;
Epidermis;
Cell cycle;
Autoradiography;
Mice;
Rats
- From:
Acta Anatomica Sinica
1953;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
By using double labelling methods with ~3H-TdR and ~(14)C-TdR, autoradiographs were prepared in young (40 days old) and in old (16 months old) male LACA mice and in adult (7～7.5 months old) female Wistar rats to observe the cell cycle time and relevant parameters of dorsal skin and both testes.The following results were obtained:1. In young and old mice, duration of cell cycle (Tc) and relevant parameters of epidermis were as follows respectively: labeling index (LI)=1.0 and 1.5％; mitotic index (MI)=0.4 and 0.4%; duration of DNA synthesis (Ts)=3.5 and 4.2 hours; Tc=20.3 and 17.5 days.In adult female rats, they were 3.0%, 0.3%, 4.7 hours and 8.3 days respectively. Tc of rat epidermis was obviously shorter than that of mouse epidermis (P0.50).
