ELECTRON MICROSCOPIC OBSERVATION ON THE EPITHELIUM IN NORMAL HUMAN ESOPHAGUS
- VernacularTitle:人正常食管上皮的电子显微镜观察
- Author:
Jun ZHANG
- Publication Type:Journal Article
- From:
Acta Anatomica Sinica
1957;0(04):-
- CountryChina
- Language:Chinese
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Abstract:
Thirty five normal esophageal mucosae were observed with electron microscopy. 11 were taken from resected esophageal specimens and 24 were obtained by using fibroendoscope biopsy forceps from normal areas of esophageal mucosae examined endoscopically.Normal esophageal epithelium is divided into basal, prickle and superficial cell layers. The continuous basement membrane separates lamina propria from basal cells. Occasionally a false rupture appears in the obliguely-cut, basement membrane.Intraepithelial lymphocytes and Langerhans cells were found in the basal cell layers and deep in the prickle cell layers. In the cell cytoplasm of one case, a few rod-shaped Langerhans granules with internal periodic substructure were observed. The Langerhans granule measures 250 nm by 50 nm. The results of our observation showed that Langerhans cells were possibly derived from intraepithetial lymphocytes.In the superficial cell layers, a large number of membrane coating granules were identified in pericytoplasm or in the cytoplasmic processes. A few granules were also found in intracellular spaces.Desmosome fields were seen in prickle cell layers. The fields were in the form of labyrinth made up of numerous desmosomes and microvillus processes. No gap junctions were found in the desmosome fields.Twisted thread-like nuclei and indented bizarre nuclei were found in both the prickle cell layers and superficial cell layers. Capillaries with fenestrated endothelium were embedded in the papillae of lamina propria.
