HISTOLOGICAL AND HISTOCHEMICAL STUDY OF RABBIT THYROID GLAND DURING THE HEALING OF EXPERIMENTAL BONE FRACTURE
- VernacularTitle:家兔实验性骨折愈合过程中甲状腺组织学及组织化学的变化
- Author:
Yixin FANG
- Publication Type:Journal Article
- From:
Acta Anatomica Sinica
1955;0(03):-
- CountryChina
- Language:Chinese
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Abstract:
Ninty-eight adult male rabbits,weighing 1.5—2.0 kg,were divided into two main groups:1,80 animals,with one segment of diaphysis,4 mm in length,sawed off from both radii,served as the experimental group;2,the rest 18 animals,without any treatment, served as controls.The thyroid glands of both groups were taken at definite time in- tervals,and subjected to histological and histochemical studies.The following results were observed: 1.The follicles of the thyroid glands of the operated animals showed an increase in size and staining reaction and decrease of the number of “vacuoles”at their periphery. The follicular cells,by statistical analysis,decreased significantly in height and in nuclear size.These changes were more pronounced between 3—17 days after the fracture,and did not recover to normal until the 35th day. 2.The histochemical reaction of RNA,ACP,ALP,NE,PO,SDH and ferric ferri- cyanide of the thyroid gland of the experimental animals were weaker than those of the normal controls,and the PAS reaction showed no changes. 3.The above results showed that after bone fracture,the functions of the thyroid gland were suppressed in different degrees at various stages. 4.The cause of the functional depression of the thyroid gland after bone fracture could be related to the decrease of secretion of thyrotropic hormone or the increase of adrenal cortical functions.
