Review on recent development of antitumor agents from Chinese herbal medicines
- Author:
Nguyen Gia Chan
- Publication Type:Journal Article
- Keywords:
Antitumor
- MeSH:
Drugs, Chinese Herbal;
Antineoplastic Agents
- From:Journal of Medicinal Materials - Hanoi
2005;10(2):35-40
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
Besides low molecular compounds against morphological and cytotoxic change that were extracted from Chinese herbal medicines, some high molecular compounds have been extracted and used for treatment of malignant disease. Among which, polysaccharides and ribosome-inactivating proteins are specially noticed. Polysaccharides from fungal and high-class plants with immunostimulation effects have been tested in experimentation and in clinical. Ribosome-inactivating proteins are a group of proteins inhibited standard protein synthesis in nucleus by attacking 28S ribosome RNA. These substances have been tested in experimental and clinical trials for treating tumor by single compound and combined with antibodies