EFFECTS OF FATIGUE ON THE DISTRIBUTION OF GLY.COGEN AND RIBONUCLEIC ACID IN THE MOUSE LIVER
- VernacularTitle:疲劳对于小白鼠肝脏的糖元及核糖核酸的影响
- Author:
Shihho CHANG
;
Hweichu YU
- Publication Type:Journal Article
- From:
Acta Anatomica Sinica
1957;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Under stimulation of electric current adult albino mice were made to run around on the wire without stop for 1 to 4 hours in a wooden case. In starved animals glycogen began to decrease 60 minutes after depri- vation of food and reached to about half within 2 to 3 1/2 hours. Six hours later only a few liver cells still contained some glycogen granules. Deple- tion of ribonueleic acid took place at a much slower rate. It broke from larger masses into tiny rods and filaments, sparsely distributed. No change of nucleus and nucleolus was noted. In exhausted animals changes of liver glycogen and ribonucleic acid were much more conspicuous than the starved ones. In most cases 2 to 3 1/2 hours' fatigue caused complete disappearance of glycogen granules and the reduc- tion of the ribonucleic acid. The chromatin condensed into larger knots or adhered to the inner side of the nuclear membrane. Central veins and sinusoids became enlarged and congested. Liver cells became smaller. Kupffer cells increased in number and their nuclei became darker.
