INFLUENCE OF STARVATION ON THE DISTRIBUTION OF PHOSPHATASES, GLYCOGEN AND RIBONUCLEIC ACID IN THE MOUSE LIVER
- VernacularTitle:绝食对小白鼠肝脏磷酸酶糖元及核糖核酸在分布上的影响
- Author:
Chene CHENG
;
Hsiaomei CHEN
- Publication Type:Journal Article
- From:
Acta Anatomica Sinica
1954;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Adult albino mice were starved for 66 to 120 hours and the liver was examined forphosphatases, glycogen and ribonucleic acid. Alkaline phosphatase was found to increasemoderately while acid phosphatase showed no significant change. Both glycogen andribonucleic acid disappeared completely. The periphery of the hepatic lobule often stainedmore deeply than the centre due mainly to the conspicuous staining of the cell borderand of the Kupffer cells. The duration of starvation had no infiuence on the amountof both alkaline and acid phosphatases. In the refeeding experiment, mice starved for 48 to 72 hours were refed and werekilled 11 to 72 hours after subjecting to normal diet. The liver cells contained even greateramount of glycogen than in control animals. The restoration of ribonucleic acid was onlypartial. Both alkaline and acid phosphatases showed variable activities in the refeedingliver. The liver cells usually swelled and became rarefied, the sinusoids were very in-conspicuous. The swelling and rarefation of liver cells were caused by the accumulationof glycogen during refeeding. Three days refeeding did not bring this histological pictureto that of the control liver.
