Retina protection effect of Huwang Mingmu San in experimental vitreous hemorrhage
- VernacularTitle:护网明目散治疗实验性玻璃体积血对视网膜保护作用的研究
- Author:
Jiaxiang XIAO
;
Yanyan WU
;
Wenmei WANG
- Publication Type:Journal Article
- Keywords:
Huwang Mingmu San(HWMMS);
Vitreous hemorrhage;
Rabbit;
Retina;
Protective effect
- From:
China Journal of Traditional Chinese Medicine and Pharmacy
2006;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:The purpose of this study was to observe Huwang Mingmu San’s(HWMMS)effect on the experimental vitreous hemorrhage.Methods:We divided 48 rabbits randomly into the A group as the normal control group,the B group as the modal group,the C group as the traditional chinese medicine group(HWMMS)and the D group as the western medicine group(entodan).Six rabbits of the four groups were killed randomly in the 8th week and their vitreous send to TNF-?,IL-6 examination at the same time.We study the activity level of MDA,SOD,NA-K-ATP enzyme on retinal.Results: It was suggested that the TNF-?’s content in HWMMS group had significantly increased than that in the normal group and the model group but no difference was found between the HWMMS group and the entodan group.Meanwhile the results showed that the HWMMS group’s content of IL-6 and MDA was lower and SOD activity,NA-K-ATP enzyme content was higher than those in the model group and the entodan group.Conclusion:We concluded that the HEMMS had a remarkable therapeutic effect on retinal damage and in promoting absorption vitreous hemorrhage.