Regulation of Recipe Xiaoban No.1 on expression of P53 in dystrophy of vulva
- VernacularTitle:消斑Ⅰ号对外阴营养不良患者皮损表皮细胞P53蛋白表达的调控作用
- Author:
Fei CHE
;
Jintu ZHU
;
Yizhi ZHENG
;
Tugen YU
;
Zhenwei XIE
;
Xiaohong YANG
- Publication Type:Journal Article
- Keywords:
Xiaoban No.1;
Chronic vulvar dystrophy;
P53;
Immunohistochemistry
- From:
China Journal of Traditional Chinese Medicine and Pharmacy
2006;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the regulation of Recipe Xiaoban No.1 on the expression of p53 in dystrophy of vulva.Methods:Expression of p53 was determined by immunohistochemical technique in skin lesion of prior treatment and posttreatment from 30 cases with chronic vulvar dystrophy,and normal skin from 23 health adults were served as controls.Results: Expression of p53 in various of chronic dystrophy of vulva before treatment was obviously higher than control group(P0.05).Conclusion:Recipe Xiaoban No.1 can obviously improve the clinical symptoms and decrease the expression rate of P53.