Effects of Danshen Injection on expression of spinal cord neurons fos and heat shock protein 70 of limb ischemia-reperfusion rats
- VernacularTitle:丹参注射液对大鼠肢体缺血再灌注损伤脊髓神经元fos、热休克蛋白70表达的影响
- Author:
Yanchun WANG
;
Jianming CHEN
;
Jun MA
- Publication Type:Journal Article
- Keywords:
Danshen Injection;
Rat;
Limb ischemia-reperfusion injury;
Spinal cord neurons fos;
HSP70
- From:
China Journal of Traditional Chinese Medicine and Pharmacy
2006;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate spinal cord neurons fos,heat shock protein 70(HSP70)change and influence of Danshen Injection after the rats’limb ischemia reperfusion.Methods:Through temporarily interdict the rat’s one side iliac artery and femoral artery to establish the model of the limb ischemia reperfusion injury.Using the immunohistochemical method of ABC to observe the expressions about neurons fos and HSP70 positive neurons and the character about their distributions,as well as their change after being intervened by Danshen Injection n.Results:The rats’spinal cord neurons fos and HSP70 expressions increased in four hours later the limb ischemia(P
