Effect of catgut implantation at acupoint and traditional Chinese medicine on cytokine in ovariectomized rats
- VernacularTitle:穴位埋线、中药对去势大鼠GM-CSF、TNF-?的影响
- Author:
Xiaoguang LUO
;
Ming JIANG
;
Nengxian LUO
- Publication Type:Journal Article
- Keywords:
Postmenopausal osteoporosis;
Catgut-acupuncture;
Bone density;
GM-CSF;
IGF-1;
TNF-?
- From:
China Journal of Traditional Chinese Medicine and Pharmacy
2006;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the effect of catgut implantation at acupoint,Compound Erxian Decoction on levels of serum cytokine in ovariectomized rats.Methods:Sixty 3-month-old female Sprague-drawley rats,weighed 230?20g each,were divided into six groups,ten rats in each group.The first group were sham-operated(Sham-G),while the remaining groups,established by excising both sides ovary,were catgut-acupuncture group(CAG),Chinese herb group(CHG),catgut-acupuncture plus Chinese herb group(CCG),estrogen group(EG)and model group(MG).There wasn’t any therapy in sham-operated group and model group.After 12 weeks corresponding therapy,all groups were sacrificed to procure blood serum for testing the contents of E 2 ,GM-CSF,IGF-1,TNF-?by means of radioimmunoassay and both retral thighbone for testing bone mineral density(BMD) and bone mineral content(BMC)in each specimen.Results:The BMD and BMC of thighbone,E 2 and IGF-1 of serum and in CAG,CHG,CCG and EG was compared with Sham-G,there was no significant difference,but which was higher than MG(P
