Non-elevated cardiovascular risk in patients with primary biliary cirrhosis and hypercholesterolemia
- VernacularTitle:原发性胆汁性肝硬化伴高脂血症患者低动脉粥样硬化危险性的原因分析
- Author:
Yisong XIONG
;
Renqian ZHONG
- Publication Type:Journal Article
- Keywords:
primary biliary cirrhosis;
hypercholesterolemia;
cardiovascular risk
- From:
Academic Journal of Second Military Medical University
2000;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
Primary biliary cirrhosis(PBC) is an autoimmune disease with unknown causes.Most PBC patients have abnormal lipid metabolism characterized by hypercholesterolemia.Paradoxically,clinical observations and pre-experimental studies showed that the risk of hyperlipidemia associated cardiovascular event and the mortality of PBC patients were not increased.In this review we summarize the possible reasons and the underlying mechanisms.