Optimization of preparation technology for pyretic arthralgia cataplasma by uniform design
- VernacularTitle:均匀设计法优选热痹巴布剂制备工艺
- Author:
Bingzhi MA
;
Hainan ZHAO
;
Wei WANG
;
Jin LU
;
Hai JU
;
Xiaoping YAN
- Publication Type:Journal Article
- Keywords:
Cataplasma;
Preparation technology;
Uniform design
- From:
China Journal of Traditional Chinese Medicine and Pharmacy
2005;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To optimize a preparation technology for pyretic arthralgia cataplasma. Methods: The preparation technology were studied by a uniform design experiment in which NP-700, tartaric acid, PVP, dihydroxyaluminum aminoacetate, glycerol, water and medicinal powder were factors and viscosity, infiltration, gel mobility and gel strength were indices. Results: The best ratio of this cataplasma matrix was NP-700:tartaric acid:PVP:dihydroxyaluminum aminoacetate: glycerol:water:powder = 4.0:0.2:1.0:0.1:25.0:35.0:2.0. According to optimized formula, to prepare the poultice, then to spread the poultice uniformly onto non-woven fabrics, cover CPP membrane and pack after 1 week at room temperature. Conclusion: Pyretic arthralgia cataplasma was well moldable and its process technology was feasible.