Study on the effect of Weichangshu Tablet on AchE and NO in rats with gastrointestinal dynamics
- VernacularTitle:胃肠舒对胃肠功能障碍大鼠胃肠道AchE及NO的影响
- Author:
Qiong LI
;
Tongshen LIU
;
Mengan LIU
- Publication Type:Journal Article
- Keywords:
Chinese traditional medicine;
Weichangshu Tablet;
Acetylcholine;
NO
- From:
China Journal of Traditional Chinese Medicine and Pharmacy
2005;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: Investigating the effect of Weichangshu on gastrointestinal motility. Methods: Divide 50 Wistar rats into 5 groups randomly:normal control, model control, low dosage of Weichangshu, high dosage of Weichangshu, Cisapride, 10 in each group.In addition to the normal control group,the other four groups were prepared animal models of gastrointestinal motility disorder;the groups were given the same volume solution of medicine by way of gastric perfusion. for seven days, samples were taken from antrum and campylobacter after animals were anesthetized.AchE,NO were showed with immunohistocheinical method by SP.The optical density of myenteric plexues were measured with mitrosperegraph. Results: groups of Weichangshu can effectively increase AchE,NOS in gastro-intestinal tractl (P
