The new methods of purinergic signalling research
- VernacularTitle:嘌呤信号转导研究的新方法
- Author:
Jun ZHANG
;
Xin LI
;
Han LIU
;
Shangdong LIANG
- Publication Type:Journal Article
- Keywords:
purinergic signaling;
FRET;
BRET;
SRET;
SELEX;
siRNA
- From:
Chinese Pharmacological Bulletin
2003;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
ATP(adenosine 5′-triphophate)is a kind of purine involved in neural transmission and regulation.With the in-depth studying about purine and pyrimidine receptor subfamilies,ATP and its receptor will become a variety of potential drug targets of disease control.The application of resonance energy transfer technology,systematic evolution of ligands by exponential enrichment in vitro and small interfering RNA technology in vivo not only expand the perspective of purinergic signaling research,but also promote their progress in disease prevention and drug screening.
