Progress in study of a novel protein Nischarin
- VernacularTitle:新型蛋白Nischarin的研究进展
- Author:
Hao MA
;
Fei LI
;
Ning WU
;
Jin LI
- Publication Type:Journal Article
- Keywords:
Nischarin;
integrin;
cell migration;
signal pathway;
I1-imidazoline receptor;
morphine dependence
- From:
Chinese Pharmacological Bulletin
2003;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Nischarin is a novel protein interacting with integrin ?5 subunit.A series of studies have indicated that Nischarin plays an important role in inhibiting tumor cells migration and invasion.Meanwhile it may also serve as the functional I1-imidazoline receptor.To study this protein will be in favour of understanding the biological mechanisms of inhibiting cell migration and developing novel drugs such as inhibitors for tumor invasion.The article mainly reviews the recent progress in studies on Nischarin.