STUDIES ON MORPHOLOGY OF LONG-TERM CULTURED PULMONARY SQUAMOUS CARCINOMA CELL LINE (LTEP-78) IN VIEW OF CLINICAL CYTOLOGY
- VernacularTitle:从临床细胞学的观点探讨人肺鳞癌细胞系(LTEP-78)的细胞形态学特征
- Author:
Yongnian QIN
- Publication Type:Journal Article
- From:
Acta Anatomica Sinica
1953;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Morphology of cells of long-term cultured pulmonary squamous carcinoma cell line (LTEP-78) and cancer cells taken from sputa of fifty lung cancer patients was studied in view of clinical cytology. The results showed that the long-term cultured cell line still have had the characteristics of squamous cell carcinoma, such as round or squamous cell outline, definite cellular border, evenness in density of cytoplasm, centrally placed nuclei and so on. On the other hand, it appeared that they have undergone some changes which resembled to adenocarcinoma cells, such as malignent signet-ring cell. We concluded, therefore, that the long-term cultured cancer cells could still keep the characteristics as cancer cells taken freshly from lung cancer patients. The differences from the fresh lung cancer cells found in cultured cells could be explained by the effects of in vitro circumstance which is quite different from that of the human body.
