Pathology of primary neuroectodermal tumor and its prognostic factors:A report of 35 cases
- VernacularTitle:35例原始神经外胚层肿瘤的病理及预后因素分析
- Author:
Lijuan CHEN
;
Yongxu JIA
;
Feifei FAN
;
Xingya LI
- Publication Type:Journal Article
- Keywords:
primary neuroectodermal tumor;
immmunohistochemistry;
survival analysis
- From:Journal of Third Military Medical University
2003;0(13):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the pathology of primary neuroectodermal tumor (PNET),and its diagnostic standards and prognostic factors.Methods Expression of CD99,FLI-1,Syn,NSE,S-100,NF,and Vim was detected in PNET tissues stained with HE and immmunohistochemistry (En Vision method).Survival rate of 33 PNET patients with complete clinical information was analyzed with COX regression analysis method.Results The positive expression rate of CD99,FLI-1,Vim,Syn,NSE and s-100 was 88.57%,51.43%,91.42%,48.57%,45.71%,and 22.86%,respectively.The sensitivity of combined CD99 and FLI-1 was 100%.However,NF was not expressed in all PNET tissues.When other factors were unchanged,no difference was found in the effect of age on the survival rate of patients.However,a significant difference was observed in the effect of PNET site and its treatment modalities on the survival rate of patients (P
