The clinical observation in the prophylactic effect of EEN on pulmonary infection in patients with severe traumatic brain injury
- VernacularTitle:重型颅脑外伤后早期肠内营养预防肺部感染的临床研究
- Author:
Yi FENG
;
Yuhai WANG
;
Zhonghua SHI
;
Jirong DONG
;
Qinyi XU
;
Xuejian CAI
- Publication Type:Journal Article
- Keywords:
Severe traumatic brain injury;
Enteral nutrition;
Pulmonary infection;
Mucosal barrier
- From:
Parenteral & Enteral Nutrition
1997;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To investigate the prophylactic effect of EEN on pulmonary infection in patients with severe traumatic brain injury.Methods: 60 cases of young adults with severe brain injury were randomized into the early enteral nutrition group(experimental group) or the control group.The experimental group was feeded 12～24 hours after injury or surgery and the control group was feeded 24 h～5 d after injury or surgery.The double-sugar test method was used for determination of intestinal barrier function,and the duration of pulmonary infection was recorded.Results: The lactulose/mannitol ratio in experimental group was significantly lower than in control group on the 7th postoperative day.The average body temperature and duration of pulmonary infection in experimental group were significantly lower than in control group.According to ADL scores,the daily capacity of convalescent patients in experimental group was significantly better than in control group.Conclusion: The early enteral nutrition can improve mucosal barrier function,reduce the incidence of pulmonary infection and improve overall prognosis in patients with severe traumatic brain injury.
