Correlation of serum C-reactive protein levels with insulin resistance in obese hyperglycemic case
- VernacularTitle:高血糖伴肥胖患者血清C反应蛋白与胰岛素抵抗的相关性研究
- Author:
Jian LUAN
;
Jietao ZHANG
;
Yanhu DONG
- Publication Type:Journal Article
- Keywords:
obesity;
hyperglycemia;
C-reactive protein;
insulin resistance
- From:
Chinese Journal of Practical Internal Medicine
2001;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the relationship between serum C-reactive protein(CRP)levels and insulin resistance(IR)in patients with hyperglycemia and obesity.Methods Fasting plasma glucose(FPG),2h plasma glucose(2hPG),fasting insulin(INS),patient height and weight were measured.Body mass index(BMI)and Homa insulin resistance index(Homa-IR)were calculated.Based on BMI and PG,the participants were divided into 4 groups:normal control group(30 cases),simple obesity group(30 cases),impaired glucose regulation(IGR)obesity group(30 cases)and type 2 diabetic obese group(30 cases).Serum C-reactive protein levels were measured with immunoturbimetric assay.Results(1)CRP and the Homa-IR in other groups were significantly increased comparing with normal control group,with statistical difference observed(P
