Experimental study of Ames test of Echinacea Herb P.E
- VernacularTitle:紫锥菊提取物的鼠伤寒沙门氏菌致突变试验研究
- Author:
Weimin DING
;
Dan ZHAO
;
Xiuyun CHEN
;
Shijin BU
- Publication Type:Journal Article
- Keywords:
Echinacea Herb P.E;
Mutagenicity;
Ames test
- From:
China Journal of Traditional Chinese Medicine and Pharmacy
2005;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To evaluate the potential mutagenicity of Echinacea Herb P.E via salmonella typhimurium Ames test. Methods:To test the Echinacea Herb P.E diffusion through Ames test. In the plate incorporation test of Salmonella Typhimurium,the average number of spontaneous revertants of TA97,TA98,TAl00,and TA102 at four concentrations was calculated after incubation at 37 ℃ for 48 hours. Results:Whether added S 9 or not,the number of induced revertants when compared to that of spontaneous revertants did not increase statistically significant. The result of Ames test was negative. Conclusion:Echinacea Herb P.E will not cause the increase of the back mutation in murine typhoid salmonella which shows that Echinacea Herb P.E will not cause gene mutation.
