Current status of diabetes research and its future
- VernacularTitle:糖尿病研究现状及展望
- Author:
Juming LU
- Publication Type:Journal Article
- Keywords:
diabetes mellitus;
hyperglycemia;
evidence-based medicine;
prevalence
- From:
Medical Journal of Chinese People's Liberation Army
2001;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the progress of diabetes research in recent years and to raise the understanding of the knowledge of diabetes.Methods Literature concerning diabetes published domestically and abroad in recent years were retrieved.The significance of advances gained in prevention and treatment of diabetes was analyzed.Results Evidence-based medicine data from a large number of multicenter clinical trials showed that general principles of intensive blood glucose control are as follows:controlling plasma glucose as early as possible,individualized strategy,and controlling other cardiovascular risks in addition to plasma glucose control.New drugs for treating type 2 diabetes were developed rapidly.Glycogon-like peptide-1 analogue and DPP-4 inhibitor have multiple effects of lowering plasma glucose and have good prospects in clinical application.Some studies indicated that gastric surgical procedure could significantly reduce hyperglycemia in excessively obese subjects with diabetes.CGM technique has become one effective method for monitoring the plasma glucose dynamically,which is helpful in controlling blood glucose.Intensive lifestyle intervention could not only prevent diabetes but also had some prolonged effects on macro-and microvascular complications of diabetes.Early intensive insulin treatment could protect the B cell function in newly diagnosed type 2 diabetes and maintain good control of blood glucose in long term.Conclusions The recent studies on diabetes have thrown important influences onto diabetes prevention and treatment.The priorities in the study in the armed forces in next 5 years may include prevention and treatment of type 2 diabetes.
