The advance role and pharmacological effects of metallothionein
- VernacularTitle:金属硫蛋白的功能及药理作用研究进展
- Author:
Yan ZHANG
;
Tingting XIAO
;
Xiangchun SHEN
- Publication Type:Journal Article
- Keywords:
metallothioneins;
function;
organ fibrosis;
tumor;
matrix metalloproteinases;
anti-oxidation
- From:
Chinese Pharmacological Bulletin
1986;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Metallothionein is a sulfhydryl-rich,and chelating a large number of metal ions,which is widely found in biological world.It is very highlighted that MT had the same physical and chemical features from different origins.Plenty of research data indicated that MTs contain 20 free sulfhydryl genes,as well as their sulfhydryl clusters,It is a multifunctional protein in health.Many experiments demonstrate that MTs may be a novel target of original new drugs because they play a role in regulating and controlling the organ fibrosis and tumor.