Targeting Nogo protein and its receptor in promoting nerve regeneration:recent progress
- VernacularTitle:以Nogo蛋白及其受体为靶点促进神经再生的研究进展
- Author:
Zhuangchen ZHU
;
Bin NI
- Publication Type:Journal Article
- Keywords:
Nogo protein;
central nervous system;
nerve regeneration
- From:
Academic Journal of Second Military Medical University
1985;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Ample evidences have showed that the failure of early regeneration of the central nervous system(CNS) in adult mammals is mainly due to the growth inhibitory factor.Efforts have been made to promote neuron regeneration and neurological function recovery by damaging myelin and removing myelin-associated inhibitors.At present,the Nogo protein associated drugs and gene therapy have become a novel effective way to promote axon regeneration after CNS injury;here we reviews the recent progress on the related issues.
