Progress in the research on the anti-cancer activity of artemisinin compounds
- VernacularTitle:青蒿素类化合物抗肿瘤研究进展
- Author:
Jinjian LU
- Publication Type:Journal Article
- Keywords:
artemisinin;
oxidative stress;
cell cycle arrest;
apoptosis;
anti-angiogenesis;
anti-cancer
- From:
Chinese Pharmacological Bulletin
1986;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Artermisinin compounds are widely used anti-malarial drugs,which also possess anti-cancer activities in various tumor cells and mouse models.It has been shown that artemisinin compounds exert their anti-cancer activity by inducing oxidative stress,cell cycle arrest,apoptosis and anti-angiogenesis activity,etc. Due to the low cytotoxicity and anti-multidrug-resistant activity,artermisinin compounds may be potentially developed for cancer therapy.
