Effect of stellate ganglion blocking on serum levels of Col,TNF-?,IL-1? and IL-6 in patients during cardiopulmonary bypass
- VernacularTitle:星状神经节阻滞对体外循环术中皮质醇、TNF-?、IL-1?、IL-6的影响
- Author:
Xiaodong ZHANG
;
Tiande YANG
;
Hong LI
- Publication Type:Journal Article
- Keywords:
stellate ganglion block;
cardiopulmonary bypass;
Col;
IL-1?;
IL-6
- From:Journal of Third Military Medical University
2003;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the effect of stellate ganglion blocking (SGB) during cardiopulmonary bypass (CPB) on inflammatory reaction.Methods Twenty patients undergoing mitral valve replacement were randomly allocated to 2 matched groups,control group and SGB group (n=10).The control group only received conventional anesthesia,while the SGB group was blocked with 1% lidocaine in addition before the operation for SBG.Blood glucose (BG),Cortisol (Col),IL-1?,IL-6 and TNF-? in the venous blood samples were detected in following 5 time points,20 min before anesthesia,20 min after anesthesia,20 min after operation,20 min afer the start of CPB and 20 min after the end of CPB.Results Col level of the control group (353.09?129.34 ng/ml) was significantly higher than that of the SGB group (486.84?152.20 ng/ml) in 20 min after the end of CPB (P
