Profilin-Ⅰand cardiovascular diseases
- VernacularTitle:Profilin-Ⅰ与心血管疾病
- Author:
Jinfang CHENG
;
Guohua NI
;
Changping HU
;
Tianlun YANG
- Publication Type:Journal Article
- Keywords:
Profilin-Ⅰ;
cardiovascular disease;
hypertension;
coronary artery disease;
diabetes mellitus;
endothelial cell;
vascular smooth muscle cells
- From:
Chinese Pharmacological Bulletin
1986;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Profilin-Ⅰis a small actin monomer-binding protein involved in regulating actin polymerization.It plays an important role in cell proliferation,differention,motility and signals transduction in different cell types including endothelial cells and vascular smooth muscle cells.This article recapitulates the wealth of information on structure,function of profilin-Ⅰand its potential role in the genesis and development of cardiovascular diseases.
