Expression of human giant larvae-1 in ovarian cancer and its clinical significance
- VernacularTitle:人源幼虫巨大致死性基因Hugl-1在卵巢癌组织中的表达及其临床意义
- Author:
Yan ZHANG
;
Xiaobo MAN
;
Chenguang BAI
;
Ning HUI
- Publication Type:Journal Article
- Keywords:
ovarian neoplasms;
Hugl-1;
gene expression;
in situ hybridization
- From:
Academic Journal of Second Military Medical University
1985;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the expression of human giant larvae-1 (Hugl-1) in ovarian carcinoma and its clinical significance.Methods Hugl-1 mRNA expression in 31 ovarian cancer and the corresponding adjacent tissues was examined by real time fluorescence quantitative RT-PCR and in situ hybridization.Moreover,analysis was done while taking into consideration of the clinicopathologic parameters of ovarian cancer.Results The expression of Hugl-1 mRNA in ovarian cancer tissue was significantly higher than that in the corresponding adjacent tissues ([0.051 ? 0.029]vs [0.026 ? 0.043],P
