Correlation between High Sensitive C-reactive Protein and Cardiac Function in Patients with Dilated Cardiomyopathy
- VernacularTitle:扩张型心肌病患者超敏C反应蛋白水平与心功能的关系
- Author:
Heng ZHOU
;
Qizhu TANG
;
Wei DENG
- Publication Type:Journal Article
- Keywords:
Dilated cardiomyopathy;
C-reactive protein;
Cardiac function;
Inflammation
- From:
Journal of Medical Research
2006;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the relationship between high sensitive C-reactive protein(hs-CRP) and cardiac function in patients with dilated cardiomyopathy(DCM). Methods We compared the differences of NYHA classes,left ventricular ejection fraction(LVEF) and left ventricular end diastolic diameter (LVEDD) between normal hs-CRP group and elevated hs-CRP group,and analyzed hs-CRP levels of different NYHA classes,then investigated the correlation between hs-CRP and LVEF and between hs-CRP and LVEDD. Results The NYHA stage,LVEF,LVEDD were 2.06?0.90,(38.58?5.98)% and 58.94?6.14mm respectively in normal hs-CRP group,while those were 2.89?0.88,(33.46?6.55)% and 66.87?9.34mm in elevated hs-CRP group,and there were significant differences between the two groups.The hs-CRP was 2.66?1.80mg/L in NYHAⅠgroup,while that was 5.02?3.27mg/L in Ⅱgroup,5.25?3.18mg/L in Ⅲ group,and 8.84?2.60mg/L in Ⅳ group.Levels of hs-CRP in Ⅱgroup and Ⅲ group were both significantly higher than those inⅠgroup(P
