Serum NO and NOS in Different Kinds of Cerebral Vascular Stenosis
- VernacularTitle:不同类型脑血管狭窄患者血清中的NO含量及NOS活性
- Author:
Jiantao LIANG
;
Zhenyu WANG
- Publication Type:Journal Article
- Keywords:
Cerebral vascular stenosis;
Atherosclerosis;
NO;
NOS
- From:
Journal of Medical Research
2006;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To search for the mechanism of NO and TNOS/iNOS in cerebral vascular stenosis,the changes of these serum factors in different kinds of cerebral vascular stenosis were studied. Methods Biochemistry assays were adopted,to analyze serum NO and TNOS/iNOS in different vascular stenosis group. Results Serum NO contents of ' Mix' (P=0.000) or ' MCA' (P=0.001) significantly increased. INOS activity of ' In' (P=0.004) and ' MCA' (P=0.002) markedly increased. And TNOS activity of ' In' group significantly weakened (P=0.032),but the TNOS activity of ' Mix' (P=0.011) and ' MCA' (P=0.018) group markedly intensified. Conclusion NO and TNOS/ iNOS partly participate in the occurrence mechanism of cerebral vascular stenosis. And the study provided theory basis for studying multiple factors of cerebral vascular stenosis.
