The Effect of CIK Cell on Apoptosis of Lung Cancer Cell A549
- VernacularTitle:CIK细胞对人肺癌细胞A549凋亡作用的影响
- Author:
Yan SHI
;
Chunjing ZHANG
;
Xiucai LIU
- Publication Type:Journal Article
- Keywords:
Cytokine induced killer cell;
Lung cancer cell A549;
Apoptosis
- From:
Journal of Medical Research
2006;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the inhibitory effects of CIK cell on apoptosis of lung cancer cell A549 in vivo. Methods CIK cells were induced by culturing PBMC with regular method and cell apoptosis was detected.Results Electron microscopic observations showed that CIK cells could induce the lung cancer cells A549 to apoptosis. Flow cytometry(FCM)demonstrated that apoptosis cells of lung cancer cells A549 were increased in CIK group as compared with the control group. Conclution CIK cells can induce the apoptosis of lung cancer cells A549.
