Effect of Stigma Maydis Aqueous Extract on Glucagon in Type 2 Diabetic Rats
- VernacularTitle:玉米须水提物对2型糖尿病大鼠胰高血糖素的影响
- Author:
Xianchun WEN
;
Li ZHOU
;
Jianfei ZHAO
;
Jicheng LIU
- Publication Type:Journal Article
- Keywords:
Stigma maydis aqueous extract;
Type 2 diabetes mellitus;
Glucagon;
Streptozotocin
- From:
Journal of Medical Research
2006;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the effect of stigma maydis aqueous extract(SMAE) on glucagon in type 2 diabetic rats.Methods Type 2 diabetic male Sprague-Dawley rat mode was induced by high-fat and high-sugar dietary feeds and low dose streptozotocin(STZ). After 8 weeks of treatment,levels of fasting blood glucose(FBG) and glucagon(Glu) in serum were respectively assayed.Immunohistocmical study was adopted to analyze the expression of glucagon in islet cells.Results Compared with model control group,SMAE of middle and high dose remarkably reduced the level of FBG and Glu(P
