Pharmacokinetics Experiment about Huanglianjiedu Decoction and Application of Data Mining
- VernacularTitle:黄连解毒汤药动学实验研究及数据挖掘技术的应用
- Author:
Zhilei QIAN
;
Mingfei ZENG
;
Huaxu ZHU
- Publication Type:Journal Article
- Keywords:
Huanglianjiedu Decoction;
active fractions;
PK-PD modeling;
Data Mining;
review
- From:
Journal of Zhejiang Chinese Medical University
2006;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
[Objective] To find the method of pharmacokinetics experiment about Huanglianjiedu Decoction.[Methods] According to references about pharmacokinetics experiments on Huanglianjiedu Decoction,the article summarized the achievements in quantitative analysis,the influence of distill techniques and pharmacokinetics on indict components in Huanglianjiedu Decoction.This article attached importance to applying the technologies of PK-PD modeling and Data Mining in research of Chinese traditional medicine compound.[Conclusion] The pharmacokinetics study on Huanglianjiedu Decoction is just in the first step; thereby further studies will be taken on this decoction in order to reveal the active fractions and effect mechanism.