Study on Co-detection of HBV Serum Immunological Markers,Pre-S1 and HBV DNA
- VernacularTitle:HBV血清标志物与Pre-S1抗原及HBV DNA联合检测研究
- Author:
Weiping LIU
;
Minggang YIN
;
Shengyu MA
- Publication Type:Journal Article
- Keywords:
Hepatitis B virus;
Pre-S1 antigen of HBV;
HBV DNA;
Fluorescence quantitative PCR
- From:
Journal of Medical Research
2006;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the correlation among HBV infection models,HBV Pre-S1 antigen and HBV DNA loads in serum and to provide evidence for the diagnosis and treatment of hepatitis B.Methods Hepatitis B markers,HBV Pre-S1 antigen and HBV DNA loads in serum samples were detected simultaneously for 1037 cases.Results The positive rate of HBV Pre-S1 antigen was higher in HBsAg,HBeAg and HBcAb positive model than that in other models(P0.05).Conclusion The quantitative detection of HBV DNA is important for the prevention of HBV infection.The combination assay of serum HBV markers,Pre-S1 antigen and HBV DNA load was beneficial to the monitoring of disease condition of hepatitis B and to the improvement of therapeutic effect.
