The Expression of Cath D,SP-A,GLUT-1 of Bronchiogenic Carcinoma
- VernacularTitle:支气管肺癌黏膜Cath D、SP-A和GLUT-1的表达及临床意义
- Author:
Huiling CAO
;
Shibing LIU
;
Xiaodong LIU
;
Pengjie XUE
;
Ye XU
;
Dandan LIU
- Publication Type:Journal Article
- Keywords:
Bronchiogenic carcinoma;
Cathepsin D;
Pulmonary surfactant-associated protein-A(SP-A);
Glucose transporter-1(GLUT-1)
- From:
Journal of Medical Research
2006;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To examine the expression of Cath D,SP-A and GLUT-1 in patients with bronchiogenic carcinoma.Methods A total of 41 patients were included in the study,10 of whom received the histological diagnosis of small cell lung cancer(SCLC).The other 28 were squamous cell carcinoma(SC) and 3 were inflammation.And all the samples were taken from the patients′ tunica mucosa bronchiorum through bronchofibroscope,then we detected the cathepsin D,SP-A and GLUT-1 following SP immunohistochemistry.Results ①Cath D: 6 samples(60%) in group SCLC were negtive expression(-6),4(40%)were moderately positive(++4),4(14%) were negative(-4),2(7%) were positive(+2),8(28%) were moderately positive(++8) and 14(50%) were intensive positive(+++14) in the other group.SCLC was significant different from SC in expressing cathepsin D(P
