The relationship between insulin resistance and Alzheimer's disease research progress
- VernacularTitle:胰岛素抵抗与阿尔茨海默病关系研究进展
- Author:
Min LI
;
Minzhe WANG
- Publication Type:Journal Article
- Keywords:
Alzheimer's disease;
cognitive impairment;
insulin resistance;
diabetes mellitus
- From:
Chinese Journal of Practical Internal Medicine
2001;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Both diabetes mellitus and cognitive impairment are frequent disorders in elderly people,Diabetes mellitus as a risk factor for stroke can cause vascular dementia.However,it is still no final conclusion whether it can cause Alzheimer' s disease or not,Most researches indicate that two diseases are positive correlation,but a few suggest no correlation between them.The brain of Alzheimer's disease has obvious phenomenon of insulin resistance,insulin and insulin sensitizers drugs can not only improve the sensitivity of insulin receptors,but also reduce the inflammatory response,promoting A?-amyloid release and clearance,benefiting of improvement in memory function.
