Study on effect of Jinxin Oral Liqiud medicated serum on early apoptosis of RSV infected cell
- VernacularTitle:金欣口服液含药血清对呼吸道合胞病毒感染细胞早期凋亡的影响
- Author:
Xia ZHAO
;
Shouchuan WANG
;
Yu HU
;
Caixia CHEN
;
Jianya XU
- Publication Type:Journal Article
- Keywords:
Respiratory syncytial virus (RSV);
Jinxin Oral Liquid (JOL);
Medicated serum;
Apoptosis;
Bcl-2;
Bax
- From:
China Journal of Traditional Chinese Medicine and Pharmacy
2005;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To study the effect of Jinxin Oral Liqiud medicated serum on RS virus virus (RSV) infected cell apoptosis and the regulation gene as Bcl-2, Bax on the different point in early time. Methods: Cell culture, serum pharmacology and Annexin V/PI technique combining with flow cytometry were used to detect cell apoptosis, Bcl-2 and Bax expression. Results: The total apoptosis rates of human embryonic lung fibroblast in JOL group in early time of 12h and 24h were significantly higher than that in RSV infected group (P