Experimental study on antiasthmafic, anti-inflammatory and immunological effects of Gubenchuansoukang Granule
- VernacularTitle:固本喘嗽康颗粒平喘、抗炎及免疫作用实验研究
- Author:
Yu GAN
;
Hong ZHANG
;
Shiju QIAO
;
Xizhuo ZHU
;
Min QIAO
;
Li MENG
;
Yulong BAO
;
Wenqi YANG
;
Linyuan FU
- Publication Type:Journal Article
- Keywords:
Gubenchuansoukang Granule;
Anti-asthma;
Anti-inflammation;
Immune
- From:
China Journal of Traditional Chinese Medicine and Pharmacy
2005;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To observe the antiasthmaf ic, anti-inflammatory and immunological effects of Gubenchuansoukang Granule. Methods: The rats asthma model was established by ovalbumin sensitization. The model was identified by the study of the asthma incubation period and the total white cells counts in bronchoalveolar lavage fluid (BALF). The anti-inflammatory effect was observed by the acute inflammation and chronic inflammation induced xylene and agar. To observe the effect of Gubenchuansoukang Granule on humoral immunity and cellular immunity induced by chicken red blood cell and 2, 4-dinitrochlorobenzene. Results: Gubenchuansoukang Granule could lengthen the asthma incubation period, reduce the quantity of total white cells in BALF, against the acute inflammation and chronic inflammation, and restrain the humoral immunity and cellular immunity. Conclusion: Gubenchuansoukang Granule had antiasthmafic, anti-inflammatory and immunosuppression effects.
