Study of the Changes of Endothelin,Tumor Necrosis Factor in Different Stress-related Gastric Mucosal Disease
- VernacularTitle:不同病因导致的应激性胃黏膜损伤及其血液ET、TNF-?的改变
- Author:
Hongliang ZHANG
;
Yang XU
;
Xiao FAN
- Publication Type:Journal Article
- Keywords:
Stress;
Ulcer index,Endothelin;
Tumor necrosis factor
- From:
Journal of Medical Research
2006;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the changes of Endothelin,Tumor Necrosis Factor in different stress; and to explore the corelation between the changes of Endothelin,Tumor Necrosis Factor and the occurrence of stress-related gastric mucosal disease.Methods The models of the acute methamidophos poison and the acute myocardial infarction in rats were made.The gastric ulcer index was counted and the content of blood plasma Endothelin and blood serum Tumor Necrosis Factor were checked.Results Models of the acute methamidophos poison and the acute myocardial infarction in rats were set up successfully. The gastric ulcer index of rats in the stress groups increased.The blood plasma Endothelin and blood serum Tumor Necrosis Factor in the stress group were significantly higher than those in the control group.Conclusion The gastric mucosal disease under different stress was observed with the gastric mucosal ulcer index.The blood plasm Endothelin and blood serum Tumor Necrosis Factor under different stress were increased,suggesting they play an important role in this phenomenen.
