Expression of Large-Conductance Calcium-sensitive Potassium Channels in Human Term Myometrium
- VernacularTitle:大电导钙敏感钾通道在人足月妊娠子宫平滑肌组织中的表达
- Author:
Ling DAI
;
Jinyan SHA
- Publication Type:Journal Article
- Keywords:
Pregnant;
Myometrium;
Parturition;
Large-conductance calcium-sensitive potassium channel;
Western blot
- From:
Journal of Medical Research
2006;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the expression of large-conductance calcium-sensitive potassium channel (BKCa) in myometrium.Methods The expression levels of BKCa ? subunit protein in human myometrium tissues in term of non-labor(TNL) and term labor(TL)were measured by Western blot analysis. Results Relative abundance of BKCa channel ? subunit protein was 1.18+0.20 for TNL group(n=9),and 0.60+0.08 for TL group(n=11).The statistic difference was significant (P=0.009). Conclusion Expression of BKCa channel protein in lower segment myometrium of TNL group was higher than that of TL group. BKCa may play a certain role in modulating uterine function.
