The Pharmacodynamic Action of Zidian Prescription on ITP
- VernacularTitle:两种制备方法的紫癜方治疗ITP模型小鼠的药效研究
- Author:
Lin ZHANG
;
Ji MA
- Publication Type:Journal Article
- Keywords:
idiopathic thrombocytopenic purpura;
Zidian prescription;
extraction process;
pharmacodynamic action
- From:
Journal of Zhejiang Chinese Medical University
2007;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
[Qbjective]To observe the effects of Zidian prescription extracted by two kinds of process on ITP mice.[Methods] Using APS to inject into mice to induce the ITP model.Mice were divided into 6 groups: C,M,DC,X,S and G groups.The number of platelet on 7th day and 14th day were measured in mice.Meanwhile the weight on 7th day and 14th day and the degree of subcutaneous bleeding were recorded.[Results]There is no significant difference in weight and the number of platelet in all groups before the experiment.Compared with the C group,the weight is in down trend in M group on 7th day,the weight and the number of platelet were declined in M group on 14th day,the petechia was more clearly in M group.Compared with the M group,the weight is up trend in DC,X,S and G groups on 7th day,the weight and the number of platelet are enhanced in DC,X,S and G groups on 14th day,the petechia was decreased in DC,S and G groups significantly.Compared with the DC group,the number of platelet is decreased in X,S and G groups.Compared with the X group,the number of platelet is increased in S and G groups.[Conclusion] Zidian prescription extracted by two kinds of extraction process has an remedial effect on ITP mouse.There is no significant difference between the two kinds of extraction process.
