Determination of Ephedrine in KMBYL Capsules by HPLC
- VernacularTitle:HPLC测定抗敏鼻炎灵胶囊中麻黄碱的含量
- Author:
Xiaoming ZHONG
;
Jingjiao ZHANG
;
Aijuan PAN
- Publication Type:Journal Article
- Keywords:
KMBYL Capsules;
Ephedrine;
'HPLC'
- From:
Journal of Zhejiang Chinese Medical University
2007;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
[Objective] To establish a method for determination of Ephedrine Hydrochloride in KMBYL capsules by HPLC.[Methods] The DiamonsilTM C18(250mm?4.6mm,5 ?m)column was used.The mobile phase was mobile phase: acetonitrine-0.02 mol?L-1potassium dihydrogen phosphate(0.2% triethylamine,adjusteding pH to 2.7 with phosphoric acid)(5∶95) with a flow rate of 1.0ml?min-1.The detection wavelength was 210 nm.The column temperature was 30℃.[Results] The linear responses range was 0.2148-2.148 ?g?mL-1 of Ephedrine Hydrochloride(r=0?9999).The average recovery was 98.85% and the RSD was 2.95%.[Conclusion] The method is simple accurate reproducible.It can be used for the quality control of KMBYL Capsules.
