Study on effect of various extract of Sini Decoction on reproductive organ and sexual hormone of hypothyroidism rats with syndrome of yang deficiency
- VernacularTitle:四逆汤不同提取液对甲减阳虚证大鼠生殖器官及性激素的影响
- Author:
Miaorong PEI
;
Xiaoying WANG
- Publication Type:Journal Article
- Keywords:
Sini Decoction;
Deficiency of yang;
Sex hormones
- From:
China Journal of Traditional Chinese Medicine and Pharmacy
2005;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study the effect of various extract of Sini Decoction on hypothalamus-pituitary-sexual glands axle of hypothyroidism rats with syndrome of yang deficiency, and discuss the mechanism of Sini Decoction in reinforcing yang. Methods: The model of deficiency of both the spleen-yang and the kidney-yang were induced by PTU solution. After the model were confirmed, the rats in Sini Decoction group were administered with Sini Decoction . At the end of the experiment, all the rats were sacrificed and the blood were sampled to check the level of Sex hormones , the reproductive organs were weighed, the testicle were sliced to check their pathological change. Results:Various extract of Sini Decoction can reduce the increase of weight of orchis and prostate of model rats, reduce their pathologic damage, and increase the level of testosterone. The alcohol extract of Sini Decoction has obvious therapetic effects. Conclusion: Sini Decoction can improve the sexual hormone level and weight index of reproductive organs of hypothyroidism rats with syndrome of yang defi ciency.
