Effect of Jianpi Shugan Huoxue Prescription on ICAM-1 gene expression in H22 hepatic cancer mice
- VernacularTitle:健脾疏肝活血方对H22肝癌小鼠ICAM-1基因表达的影响
- Author:
Dongsheng ZHENG
;
Xiaowei ZHENG
;
Yongjun ZHANG
- Publication Type:Journal Article
- Keywords:
Hepatic cancer;
Jianpishuganhuoxuefang;
Intercellular adhesion molecule-1;
Gene expression
- From:
China Journal of Traditional Chinese Medicine and Pharmacy
2005;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To discuss the effect of Jianpi Shugan Huoxue Prescription on ICAM-1 gene expression in H22 hepatic cancer mice. Methods: Animal model of H22 hepatic cancer mice were established by inoculating tumor cell. Mice were randomly divided into six groups: the normal group, the model group , Cyclophosphamide group, low, middle and high dosage groups of Jianpi Shugan Huoxue Prescription. The gene expression of ICAM-1 were detected by reverse-transcription polymerase chain reaction (RT-PCR). Results: Compared with model group, the contents of ICAM-1 in serum in the middle and high dosage groups of Jianpi Shugan Huoxue Prescription both decreased(P
