The role of autophagy in maintaining pancreatic beta-cell function
- VernacularTitle:自噬对维持胰岛B细胞正常功能的作用
- Author:
Jie WU
;
Dajin ZOU
- Publication Type:Journal Article
- Keywords:
autophagy;
pancreatic beta-cell;
type 2 diabetes
- From:
Academic Journal of Second Military Medical University
1999;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
Disrupted pancreatic ?-cell function and decreased ?-cell number are two of the main causes of type 2 diabetes mellitus.Recent studies have indicated that autophagy plays an important role in protecting pancreatic ?-cell and in maintaining the structure,number,and secretive function of pancreatic ?-cell.Although autophagy has been a focus of study in recent years,including areas such as tumor,neural diseases and aging,but its relationship with pancreatic ?-cell was not included.In this paper we review the concept of autophagy and its role in maintaining the normal function of pancreatic ?-cells.
