Anti-thyroid drugs—first choice for Graves' disease
- VernacularTitle:抗甲状腺药物治疗——Graves病治疗的首选
- Author:
Shu WANG
- Publication Type:Journal Article
- Keywords:
Graves' disease;
hyperthyroidism;
anti-thyroid drugs;
treatment with radioiodine
- From:
Chinese Journal of Practical Internal Medicine
2003;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Graves' disease,the most common disorder of hyperthyroidism,is an autoimmune disease related with autoantibody (TRAb),with the specific mechanism remaining incompletely understood.The therapies for Graves disease include three conventional methods:anti-thyroid drugs,radioiodine and surgery.Only treatment with anti-thyroid drugs is aimed at the immune factor;they can eliminate TRAb and lead to recovery ultimately.Literatures have drumed in that treatment with anti-thyroid drugs was a basic therapy for Graves' diseases,and they were the first choice to cure hyperthyroidism all over the world (except for the U.S.A).The drugs do not destroy the structure of thyroid follicle,and are safe and efficient;moreover,their effect is reversible and therefore do not cause permanent damage to the thyroid.Anti-thyroid drugs not only can be used alone,it also can be used before radioiodine or surgery.ATA chairman professor Cooper(NEJM,2005) propounded a therapy path for Graves' disease,which is helpful for clinical practice.
